Answer: Unfortunately, based on your description, I am unable to specifically diagnose the problem with your barberry. This is normally a trouble free plant! However, it is possible that it is infected with a fungus or disease such as verticillium wilt which can cause leaf drop much as you described. Since the normal recommendation for verticillium would be to remove the infected plant and the soil around it, you might wish to consult with your county extension (272-7241) for a more exact diagnosis and suggested remedies, if any.
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