Answer: Mimosas can be pruned, however each cut you make offers an invitation for pests and diseases to enter the bark. Since mimosas are potentially subject to so many problems, it is usually better to avoid pruning if possible. If you really want to prune, the best time would be late winter to early spring before it starts to grow for the year, or early summer when the cuts will heal fastest. Pruning in early summer will reduce the number of blooms however. Enjoy your mimosa!
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