Answer: Yes, an established rose bush can up and die suddenly - but there is usually a reason, whether or not it is immediately apparent. If the stems look healthy but are not producing leaves, there may be some winter dieback. Prune the plant back to where you see new growth. If only one half of the plant is affected, it might be a root problem - caused by either insects or disease. You may want to dig the plant and inspect the root system and lower part of the shrub. Perhaps you'll see holes from boring insects or galls on the roots or even rotted roots. If this is the case, the rose bush should be replaced. Wish I had better news for you!
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