Answer: Round Up is a vegetation killer so if you use it in your flower beds it may also kill your flowers. If there are a lot of weeds you may want to remove your perennial plants and rework the bed to not only remove the weeds but to also incorporate some organic matter to loosen and enrich the soil. After removing your plants and pulling all visible weeds (roots and all!), spread 4-5 inches of organic matter over the soil. Use compost or aged manure or whatever is locally available. Dig it in to a depth of 8-10 inches, level the soil and replant your perennials. You can then sprinkle a pre emergent herbicide over the bare soil (Preen, or another corn gluten based pre emergent) and cover over that with mulch. You bed should remain weed free all season long.
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