This is an interesting discussion ! I thought "heirloom seeds" were, like Caroline said, OP varieties that had been maintained for many years in a family or community and handed down from one generation to the next... but, when in doubt I tend to Google, and a quick search showed this description the Clemson Univ. website:
"Heirloom vegetables are defined in several ways. Some consider heirlooms to be any vegetable cultivars that have been grown for a certain length of time. Other people consider vegetables to be truly heirlooms only if being passed down by a family or group has preserved them. Heirlooms are always open-pollinated, since hybrid seed can not be maintained by ordinary means. However heirloom vegetables are defined, interest is increasing in our edible heritage."
And even Burpee says "Heirloom varieties are open-pollinated--meaning that unlike hybrids, seeds you collect from one year will produce plants with most of the characteristics of the parent plant. And that's key to their survival."
And also found the fact that Burpee's Big Boy hybrid tomato was first introduced in 1949 (and that wasn't the first hybrid introduction by any means).
So, wouldn't most (or maybe all?) hybrids have originally been the product of combining "heirloom" varieties?