Don't forget, people that take care of plants for a living are spraying - and wearing and breathing - whatever they're using all day on hundreds or acres of plants, not just a few like you and me. Even if most of the sprays used are 'natural' or even 'organic' I wouldn't want to ingest or absorb it all day through my skin. Those lawn care services that come around and spray stuff on people's lawns should probably require their employees to wear protective clothing, glasses and masks, too.
I wear long sleeves and long pants, a hat and safety glasses even to use my little battery-powered leaf blower. Never know what's going to fly up and get on you, in your hair or eyes. Sometimes I wish I'd worn a little filter mask, too. When you blow your nose and what comes out is black . . . ick.
I sprayed my mango tree with a scent deterrent called 'Critter Ridder' to try to discourage the squirrels. It's a combination of stuff like black pepper and cayenne. Nothing toxic, but WoW did my eyes and nose ever burn after spraying the whole tree, and I was careful, too. I was sneezing for an hour afterwards and had to shower and put on fresh clothes to get rid of it off me.