I always used Round-Up to kill Poison Ivy. Bayer has a product available now that I am using instead. That is pretty much the extent of my weed killing.
The rest of the weeds are getting away from me too. But the biggest pain in the rear is all the seedlings from the Rose of Sharon. I thought I would leave two large ones when I made the garden in back of the house since I love seeing their blooms right outside the kitchen windows. Now I have hundreds of seedlings in among my iris. I am constantly wacking them with my Cobra Head.