Hello Bigant,
Welcome to the National Gardening Association. Since the lower leaves seem to be in trouble and the newer leaves look pretty good, I suspect a nutrition problem. Plants that have a shortage of some nutrients will "steal" those nutrients from the older growth to use for the newer growth. So lots of detail about the nutrients would be appropriate.
Incidentally, Calcium is also an essential macronutrient (plants need quite a lot of it right after the usual Nitrogen, Phosphorous, and Potassium) I use Calcium nitrate as a component of my indoor nutrients. It is available at most hydroponic grower suppliers. I supply Magnesium via Epsom Salts (Magnesium sulfate) available at most supermarkets and pharmacies. Both Magnesium and Sulfur are vital elements for plants. Plants also need several "trace" elements. Just out of curiosity, what is your water supply? (Plants don't need Fluorine.)
I know that plants need only the red and blue light, but they mix to a hideous purple. I suggest you switch to white grow lights for your own pleasure.
ZM