Mrs is an ex-Mainuh and her folks still live there, in the mid-coast area near Rockland.
FWIW, you might want to take the I-81 exit off of I-80 in PA, go north to Scranton, pick up I-84 to I-90 in MA, then I-90 to I-495 north, to avoid Boston traffic, follow that to I-95, which will take you right up to Maine. That's our usual route and we've done it many times, both by car and by truck.
Have a great trip which ever way you go
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