Thanks CPPgardener! Here is a photo of the whole plant, another closer up to show the (good?) condition about halfway up the plant, and one of the base. It was in this self-watering pot when I bought it, which has no drainage holes in the bottom - I've never relied on the self-watering part, just watered once every couple weeks. Responses to your questions:
Where do you live? Toronto, Canada
How do you decide when to water? When top inch of soil is dry.
Does the pot have drain holes? I'm guessing it does since you've had it so long, but you never know! No it does not! I don't know what is in the bottom of the pot. It's an IKEA pot the previous owner had it in.
When you water does much come out of the bottom? N/A
Have you fertilized it? If so, with what and how much/often? I did once in the middle of the summer with MiracleGro for indoor plants (blue crystals dissolved in water). I may have done that again this autumn but don't remember now.
How close to a window is it?
What direction does the window face? It's about 7 feet from the nearest window. Window faces roughly west. The plant doesn't really get direct sunlight though because of where it is in the corner of the room, not right in the path of the sunlight.
Did something change before the leaves started dropping?
Could a household cleaning product have been spilled in it? I don't think anything really changed but maybe the season. It was growing vigorously in the summer in this location. I did treat it for aphids shortly after buying it, with a low concentration of dish detergent in water, and thoroughly rinsed all the leaves after with wet cloths (or at least it seemed thorough to me).
Is it just the tallest stem or is it all over? Unfortunately it is affecting all the stems, not just the tallest one. It affects lower leaves and higher ones, too.
Thank you again!