What specific plants or is it a whole general area? Flowers, bushes, vegetables or trees? 3 in 1 is a systemic can get into flower buds and harm bees. Just like most things timing is everything. If you need drastic measures usually take them when plants are more dormant. If I have something in a rose cane that needs a systemic I do it before bloom season. That way pollinators are not affected. Neem oil is good but if it's too hot out it fries your plants. If you can make it through this season with soap, in the fall, winter and very early spring use neem oil spray saturate the ground around your plants. That is where insects can also over winter. May you find a good solution and have joy in your heart.
