Cindy,
I have never sprayed a tomato in my life. Worst bug I get is what we call garbage bugs. Little black beetles that get into a crack and eat away.
Sandy,
I've had blighted leaves the last couple of years. I stake mine, so they don't get a lot of splash from rain, but apparently enough. I also took off bottom branches that don't bear anyway.
Still ripening fruit. We are down to 5 green tomatoes in a bowl and I think only one is going to change color.