If you use a poison like Sevin, I recommend using it at dusk after bees and butterflies have left the area. Try to spray it on the leaves rather than the flowers. It it gets into the flowers it will poison the beneficial pollinating bees, butterflies, and hummingbirds who return the next day to consume nectar. Even if you just spray the leaves, it will still kill other beneficial insects, like ladybugs that are present, and pollinating leafcutter bees who return the next day.