I initially set up our dome greenhouse with raised beds on both sides of the water holding tank. It was a job building, insulating, and filling the beds. It took an incredible amount of soil mix to fill them. Then when growing, if a plant needed treatment, it was hard to treat it without spraying the glazing or hurting other plants. If you have container plants it's much easier to remove them, treat them or quarantine them.
I'm now thinking of removing one raised bed so I can have shelves for plants. I think that would be much easier for me to manage. It will be awhile though, as we both have to recover our health and strength.