I do not know how your weather is like. Every locale is different, but for example, on my side, we got back to colder than what Adeniums like so it promptly dropped some of its leaves. But is now growing new ones. I have stopped doing watering and just let it feel the change in temps. Thankfully the caudex is staying firm. It is now growing slowly again a new batch of leaves.
I do agree your media looks too heavy and dense. I would improve that and make it much more grittier and well draining than that. It will also give you the chance to inspect the root zone and see what is going on below soil level.
Trim off all the obviously dead branches, and dab some light cinnamon on the exposed cut. Give it time to recover. Watering it twice a week is too often if your temps is not yet consistently hitting 90F and higher. So be very, very careful with watering. So I would improve the media first, make it grittier, water it thoroughly at least once a week, positioned in full sun.
