Since the op wanted to know what didn't work for those over 50, I have to say I think I have found what does work for me and already discarded what doesn't. And, being welllllll over 50, I can't always remember what most of those discarded tools were.
I know what does work for me, my cobra head weeders, long and short handled, are the perfect angle for me to comfortably use. Bahco hand pruners come in different sizes and, for me, the small size is easy on my arthritic hands. My Felco's work beautifully but they are heavy and a bit too large to be comfortable for a long period of time.