Actually, I heavily amended the back half of my big raised bed with a lot of acidic stuff for them, so they are "more or less" in the ground, but raised up out of the alkaline pure sand that the rest of the yard is full of.
That's the key for blueberries, keeping the soil pH low enough for them. I'm sifting my compost and mixing it with peat moss for amendment every spring.
Well then once you get them producing, it's a whole new set of keys - how to keep from sharing all your berries with mice, rats, squirrels, bunnies, birds, other people, bugs . . . will cross that bridge if I ever get there. I got about a handful of berries this year, and they were yummy! Only one bush out of 6 actually set fruit. Next year!!