Since bees....honey, mason,or bumble....are insects, ANY insecticide will hurt them! Here (and I have lots of bees, since we are "beekeepers") I seldom, if ever, see a bee on an iris blossom.....until late in the year, when the 'rebloomers" are blooming. The reason, I think, is there are so many OTHER blossoms that tempt the bees more in the spring . And, since I have my iris in beds, by themselves, with no other flowers, I feel pretty safe using insecticides (systemic or contact) on my iris, in the spring. Later, for the rebloomers, I use other methods.
I think the "key" to using any *garden chemical* (and this also applies to those "organic controls", that supposedly safe for pets and wildlife) is to only use what you NEED to use, follow ALL the directions, only use it at the 'proper time" to control what you are *targeting*, and THINK , and do your research , before you use them .